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Project

Research Project for Practical Applications of Regenerative Medicine under the Japan Agency for Medical Research and Development (AMED)
“Realization of regenerative medicine through allogeneic chondrocyte sheets for the treatment of osteoarthritis of the knee”

Under this grant program, our aim is to complete the treatment of ten patients (eight patients remaining) as approved in our provision plan for Class I Regenerative medicine conforming to the new 2014 Act on the Safety of Regenerative Medicine. Our goals are to confirm safety through the clinical study and to also evaluate and verify efficacy of allogeneic chondrocyte sheets.

Research Center Network for Realization of Regenerative Medicine -The Program for Technological Innovation of Regenerative Medicine
“Study of chondrocyte sheets derived from induced pluripotent stem cells for accelerated establishment of a regenerative treatment for articular cartilage”

Under this grant program, our aim is to establish preclinical proof-of-concept of a novel cell source, iPS cell derived cartilaginous tissue, for the fabrication of chondrocyte sheets. iPS cell derived cartilaginous tissue was developed by Tsumaki Lab at the Center for iPS Cell Research and Application (CiRA) at Kyoto University. We are currently investigating the use of iPS cell derived cartilaginous tissue fabricated from iPS cells developed for clinical use in the iPS Cell Stock Project.

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Video introduction for the allogeneic transplantation of chondrocyte sheets

Our reseach was introduced on a news program in Taiwan

Our research was introduced on NHK World TV

UMIN CTR