Project
Research Project for Practical Applications of Regenerative Medicine under the Japan Agency for Medical Research and Development (AMED)
“Completion of the Advanced Medical Care through autologous cell sheet transplantation targeting osteoarthritis of the knee”
Under this grant program, our aim is to complete the ongoing clinical study “Articular cartilage regeneration through autologous cell sheets” under the plan for Class II regenerative medicine to confirm the safety and efficacy of this treatment and to continue our efforts in the realization of this treatment for the treatment of cartilage defects associated with Osteoarthritis of the knee (OAK). For the purpose of the widespread use of this treatment, we will analyze data on efficacy and safety so that this advanced medical care will be covered by national health insurance.
Research Project for Practical Applications of Regenerative Medicine under the Japan Agency for Medical Research and Development (AMED)
“Realization of regenerative medicine through allogeneic chondrocyte sheets for the treatment of osteoarthritis of the knee”
Under this grant program, our aim is to complete the treatment of ten patients (eight patients remaining) as approved in our provision plan for Class I Regenerative medicine conforming to the new 2014 Act on the Safety of Regenerative Medicine. Our goals are to confirm safety through the clinical study and to also evaluate and verify efficacy of allogeneic chondrocyte sheets.
Research Project for Practical Applications of Regenerative Medicine under the Japan Agency for Medical Research and Development (AMED)
“Physician-initiated clinical trial to evaluate the efficacy of intra-articular injection of platelet-rich plasma (PRP) for osteoarthritis of the knee: A Multicenter, Randomized, Double-blind, Placebo Controlled, Clinical Trial”
Under this grant program, we will conduct a physician-initiated clinical trial for Japanese patients with osteoarthritis of the knee (OAK) using Platelet Rich Plasma (PRP) produced from domestic isolation devices in a multicenter, blinded, clinical comparative study to verify efficacy. In addition, as an accompanying research, biomarkers related to efficacy will be explored and identified.
