研究論文
細胞シート(Cell Sheet)
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Wasai S, Toyoda E, Takahashi T, Maehara M, Okada E, Uchiyama R, Akamatsu T, Watanabe M,
Sato M
Development of Injectable Polydactyly- Derived Chondrocyte Sheets.
Int J Mol Sci, 22(6),2021.
- 浜橋恒介,佐藤正人
変形性膝関節症に対する関節軟骨再生医療 自己・同種軟骨細胞シート移植の安全性と有効性について.
整形外科Surgical Technique,11(3),117-121,2021.6
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Takizawa D, Sato M, Okada E, Takahashi T, Maehara M, Tominaga A, Sogo Y, Toyoda E,
Watanabe M
Regenerative effects of human chondrocyte sheets in a xenogeneic transplantation model using immune‐deficient rats.
J Tissue Eng Regen Med, [Epub ahead of print] 2020.
- Hayashi A, Maehara M, Uchikura A, Matsunari H, Matsumura K, Suong-Hyu H, Sato M
Development of an efficient vitrification method for chondrocytesheets for clinical application.
Regenerative Therapy, 14, 215-221, 2020.
- 佐藤正人
細胞シートによる関節軟骨の再生医療 -臨床研究・先進医療-.
再生医療, 19(2), 142-148, 2020.
- Toyoda E, Sato M, Takahashi T, Maehara M, Okada E, Wasai S, Iijima H, Nonaka K, Kawaguchi Y, Watanabe M
Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration.
International Journal of Moleculer Sciences, 21(1):E149, 2019.
- Sato M, Yamato M, Mitani G, Takagaki T, Hamahashi K, Nakamura Y, Ishihara M, Matoba R, Kobayashi H, Okano T, Mochida J, Watanabe M
Combined surgery and chondrocyte cell-sheet transplantation improves clinical and structural outcomes in knee osteoarthritis.
NPJ Regen Med, 4, 4, 2019.
- Takatori N, Sato M, Toyoda E, Takahashi T, Okada E, Maehara M, Watanabe M
Cartilage repair and inhibition of the progression of cartilage degeneration after transplantation of allogeneic chondrocyte sheets in a nontraumatic early arthritis model.
Regenerative Therapy, 9, 24-31, 2018.
- 浜橋恒介, 佐藤正人, 三谷玄弥, 高垣智紀, 芹ヶ野健司, 横山美由希, 谷良樹, 渡辺雅彦
早期KOAに対する軟骨細胞シートの可能性.
THE BONE, 32(1), 109-112, 2018.
- 前原美樹, 豊田恵利子, 高橋匠, 佐藤正人
細胞シートによる関節軟骨再生医療とガラス化保存技術の開発.
膜, 43 (2), 50-55, 2018.
- Tominaga A, Sato M, Takahashi T, Toyoda E, Toyoda K, Suzuki T, Takahashi M, Watanabe M, Okazaki K
Quality assessment of cellular and tissue-based products using liquid chromatography-tandem mass spectrometry.
Biochem Biophys Res Commun, 496(2), 429-435, 2018.
- 佐藤正人
東海大学で実施している軟骨再生医療(臨床研究)について.
杏子(秦野伊勢原医師会広報), 46(12), 188-190, 2018.
- Maehara M, Sato M, Toyoda E, Takahashi T, OkadaE, Kotoku T, Watanabe M
Characterization of polydactyly-derived chondrocyte sheets versus adult chondrocyte sheets for articular cartilage repair.
Inflamm Regen, 37:22, 2017.
- Maruki H, Sato M, Takezawa T, Tani Y, Yokoyama M, Takahashi T, Toyoda E, Okada E, Aoki S, Mochida J, Kato Y
Effects of a cell-free method using collagen vitrigel incorporating TGF-β1 on articular cartilage repair in a rabbit osteochondral defect model.
J Biomed Mater Res B Appl Biomater, 105(8), 2592-2602, 2017.
- 佐藤正人
自己および同種細胞シートによる関節軟骨再生医療と再生医療新法への対応.
日本整形外科学会誌(J.Jpn.Orthop.Assoc), 91, 217-222, 2017.
- 浜橋恒介, 佐藤正人, 三谷玄弥, 高垣智紀, 横山美由紀, 谷良樹, 豊田恵利子, 渡辺雅彦
同種軟骨細胞シートによるOA治療の可能性.
分子リウマチ治療, 10(2), 24-27, 2017.
- 佐藤正人
細胞シートによる関節軟骨再生治療.
Progress in medicine 基礎・治療, 37(5), 55-59, 2017.
- Tani Y, Sato M, Maehara M, Nagashima H, Yokoyama M, Yokoyama M, Yamato M, Okano T, Mochida J
The effects of using vitrified chondrocyte sheets on pain alleviation and articular cartilage repair.
J Tissue Eng Regen Med, 11(12), 3437-3444, 2017.
- Kokubo M, Sato M, Yamato M, Mitani G, Uchiyama Y, Mochida J, Okano T
Characterization of layered chondrocyte sheets created in a co-culturesystem with synoviocytes in a hypoxic environment.
J Tissue Eng Regen Med, 11(10), 2885-2894, 2017.
- Toyoda E, Sato M, Takahashi T, Maehara M, Mochida J
Application of chondrocyte sheet for cartilage regeneration.
Stem Cell Research & Therapeutics, 1(1), 2016.
- Yokoyama M, Sato M, Mitani G, Takagaki T, Yokoyama M, Okada E, Kokubo M, Yamato M, Ito N, Takaku Y, Murai K, Matoba R, Akutsu H, Yamato M, Okano T, Mochida J
Assessment of the Safety of Chondrocyte Sheet Implantation for Cartilage Regeneration.
Tissue Engineering part C Methods, 22(1), 59-68, 2015.
- 豊田恵利子, 佐藤正人, 持田譲治
細胞シートによる関節治療を目指したヒト幹細胞臨床研究.
日本臨牀, 73(増刊号5, 再生医療‐新たな医療を求めて‐), 504-508, 2015.
- 佐藤正人
変形性膝関節症の軟骨再生治療.
月刊 細胞‐The Cell‐, 47(8)臨時増刊号, 14-17, 2015.
- 浜橋恒介, 佐藤正人, 高垣智紀, 三谷玄弥, 持田譲治
温度応答性培養皿を用いて作製した軟骨細胞シートの関節軟骨再生効果.
関節外科 34(5), 58-61, 2015.
- 佐藤正人
【誌説】実験ノート.
整形外科 65(10), 1034, 2014.
- 佐藤正人
セルシートエンジニアリング, 関節軟骨再生.
最新医学 69(7月増刊号), 144-153, 2014.
- 佐藤正人
細胞シートによる関節治療の再生医療.
日本臨牀 72(増刊号3), 722-727, 2014.
- Sato M, Yamato M, Hamahashi K, Okano T, Mochida J
Articular cartilage regeneration using cell sheet technology.
The Anatomical Record 297(1), 36-43, 2014.
- 佐藤正人
関節治療を加速する細胞シートによる再生医療の実現.
日本再生医療学会誌 13(1), 64-68, 2014.
- 佐藤正人
軟骨再生医療の現状・今後の展望.
日本機械学会誌 117(1142), 16-19, 2014.
- Takaku Y, Murai K, Ukai T, Ito S, Kokubo M, Satoh M, Kobayashi E, Yamato M, Okano T, Takeuchi M, Mochida J, Sato M
In vivo cell tracking by bioluminescence imaging after transplantation of bioengineered cell sheets to the knee joint
Biomaterials 35(7) 2199-2206, 2014.
- Mitani G, Sato M, Yamato M, Kokubo M, Takagaki T, Ebihara G, Okano T, Mochida J
Potential utility of cell sheets derived from the anterior cruciate ligament and synovium fabricated in temperature-responsive culture dishes.
J Biomed Mater Res A, 102(9), 2927-2933, 2014.
- 佐藤正人
細胞シートによる関節軟骨の治療.
CLINICAL CALCIUM 23(12), 59-65, 2013.
- Maehara M, Sato M, Watanabe M, Matsunari H, Kokubo M, Kanai T, Sato M,
Matsumura K,Hyon SH, Yokoyama M, Mochida J, Nagashima H
Development of a novel vitrification method for chondrocyte sheets.
BMC Biotechnol 13(58), 2013.
- 佐藤正人
細胞シートによる関節軟骨再生治療.
Pharma Medica 31(4), 15-19, 2013.
- 佐藤正人, 持田讓治
細胞シート技術を応用した軟骨再生法の開発.
整形・災害外科 56(5), 565-572. 2013.
- Kokubo M, Sato M, Yamato M, Mitani G, Kutsuna T, Ebihara G, Okano T, Mochida J
Characterization of chondrocyte sheets prepared using a co-culture method with temperature-responsive culture inserts.
J Tissue Eng Regen Med, Published online 2013, 10(6), 486-495, 2016.
- Hamahashi K, Sato M, Yamato M, Kokubo M, Mitani G, Ito S, Nagai T, Ebihara G,
Kutsuna T, Okano T, Mochida J
Studies of the humoral factors produced by layered chondrocyte sheets.
J Tissue Eng Regen Med, 9(1), 24-30, 2012.
- Ito S, Sato M, Yamato M, Mitani G, Kutsuna T, Nagai T, Ukai T, Kobayashi M, Kokubo M, Okano T, Mochida J
Repair of articular cartilage defect with layered chondrocyte sheets and cultured synovial cells.
Biomaterials 33(21), 5278-5286, 2012.
- Ebihara G, Sato M, Yamato M, Mitani G, Kutsuna T, Nagai T, Ito S, Ukai T, Kobayashi M, Kokubo M, Okano T, Mochida J
Cartilage repair in transplanted scaffold-free chondrocyte sheets using a minipig model.
Biomaterials 33(15), 3846-3851, 2012.
- 高久裕子, 村井邦彦, 鵜養 拓, 伊藤 聡, 小久保舞美, 小林英司, 竹内 護, 持田讓治, 佐藤正人
ラット膝関節内へ移植した細胞シートのBioluminescenceによる経時的評価.
臨床整形外科 47(1), 27-31, 2012.
- 佐藤正人, 三谷玄弥, 伊藤 聡, 鵜養 拓, 小久保舞美, 持田讓治
【総説】分子レベルからみた整形外科疾患-シリーズⅧ, 関節軟骨損傷修復のための軟骨細胞シート.
整形・災害外科 53(13), 1554-1555, 2010.
- Mitani G, Sato M, Lee JI, Kaneshiro N, Ishihara M, Ota N, Kokubo M, Sakai H, Kikuchi T, Mochida J
The properties of bioengineered chondrocyte sheets for cartilage regeneration.
BMC Biotechnology 9(17), 2009.
- Kaneshiro N, Sato M, Ishihara M, Mitani G, Sakai H, Kikuchi T, Mochida J
Cultured articular chondrocytes sheets for partial thickness cartilage defects utilizing temperature-responsive culture dishes.
European Cells and Materials13, 87-92, 2007.
- 三谷玄弥, 佐藤正人, 持田讓冶
細胞シート工学.
臨床雑誌 整形外科 58(2), 216, 2007.
- Kaneshiro N, Sato M, Ishihara M, Mitani G, Sakai H, Mochida J
Bioengineered chondrocyte sheets may be potentially useful for the treatment of partial thickness defects of articular cartilage.
Biochemical and Biophysical Research Communications 349(2), 723-731, 2006.
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