研究論文
細胞シート（Cell Sheet）
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Hamahashi K, Toyoda E, Ishihara M, Mitani G, Takagaki T, Kaneshiro N, Maehara M, Takahashi T, Okada E, Watanabe A, Nakamura N, Kato R, Matoba R, Takagi T, Akutsu H, Umezawa A, Kobayashi H, Akamatsu T, Yamato M, Okano T, Watanabe M, and Sato M
Polydactyly-derived allogeneic chondrocyte cell-sheet transplantation with high tibial osteotomy as regenerative therapy for knee osteoarthritis
npj Regen Med, 7, 1, 2022.
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Kondo M, Kameishi S, Kyungsook Kim K, Nicolas F. Metzler, Travis G. Maak, Douglas T. Hutchinson, Angela A. Wang, Maehara M, Sato M, David W. Grainger & Okano T
Safety and efficacy of human juvenile chondrocyte-derived cell sheets for osteochondral defect treatment
npj Regen Med, 6, 65, 2021.
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Wasai S, Toyoda E, Takahashi T, Maehara M, Okada E, Uchiyama R, Akamatsu T, Watanabe M,
Sato M
Development of Injectable Polydactyly- Derived Chondrocyte Sheets.
Int J Mol Sci, 22(6), 2021.
- 浜橋恒介，佐藤正人
変形性膝関節症に対する関節軟骨再生医療 自己・同種軟骨細胞シート移植の安全性と有効性について.
整形外科Surgical Technique,11(3),117-121,2021.6
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Takizawa D, Sato M, Okada E, Takahashi T, Maehara M, Tominaga A, Sogo Y, Toyoda E,
Watanabe M
Regenerative effects of human chondrocyte sheets in a xenogeneic transplantation model using immune‐deficient rats.
J Tissue Eng Regen Med, 14(9), 1296-1306, 2020.
- Hayashi A, Maehara M, Uchikura A, Matsunari H, Matsumura K, Suong-Hyu H, Sato M
Development of an efficient vitrification method for chondrocytesheets for clinical application.
Regenerative Therapy, 14, 215-221, 2020.
- 佐藤正人
細胞シートによる関節軟骨の再生医療 -臨床研究・先進医療-.
再生医療, 19(2), 142-148, 2020.
- Toyoda E, Sato M, Takahashi T, Maehara M, Okada E, Wasai S, Iijima H, Nonaka K, Kawaguchi Y, Watanabe M
Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration.
International Journal of Moleculer Sciences, 21(1):E149, 2019.
- Sato M, Yamato M, Mitani G, Takagaki T, Hamahashi K, Nakamura Y, Ishihara M, Matoba R, Kobayashi H, Okano T, Mochida J, Watanabe M
Combined surgery and chondrocyte cell-sheet transplantation improves clinical and structural outcomes in knee osteoarthritis.
npj Regen Med, 4, 4, 2019.
- Takatori N, Sato M, Toyoda E, Takahashi T, Okada E, Maehara M, Watanabe M
Cartilage repair and inhibition of the progression of cartilage degeneration after transplantation of allogeneic chondrocyte sheets in a nontraumatic early arthritis model.
Regenerative Therapy, 9, 24-31, 2018.
- 浜橋恒介, 佐藤正人, 三谷玄弥, 高垣智紀, 芹ヶ野健司, 横山美由希, 谷良樹, 渡辺雅彦
早期KOAに対する軟骨細胞シートの可能性.
THE BONE, 32(1), 109-112, 2018.
- 前原美樹, 豊田恵利子, 高橋匠, 佐藤正人
細胞シートによる関節軟骨再生医療とガラス化保存技術の開発.
膜, 43 (2), 50-55, 2018.
- Tominaga A, Sato M, Takahashi T, Toyoda E, Toyoda K, Suzuki T, Takahashi M, Watanabe M, Okazaki K
Quality assessment of cellular and tissue-based products using liquid chromatography-tandem mass spectrometry.
Biochem Biophys Res Commun, 496(2), 429-435, 2018.
- 佐藤正人
東海大学で実施している軟骨再生医療（臨床研究）について.
杏子（秦野伊勢原医師会広報）, 46(12), 188-190, 2018.
- Maehara M, Sato M, Toyoda E, Takahashi T, OkadaE, Kotoku T, Watanabe M
Characterization of polydactyly-derived chondrocyte sheets versus adult chondrocyte sheets for articular cartilage repair.
Inflamm Regen, 37:22, 2017.
- Maruki H, Sato M, Takezawa T, Tani Y, Yokoyama M, Takahashi T, Toyoda E, Okada E, Aoki S, Mochida J, Kato Y
Effects of a cell-free method using collagen vitrigel incorporating TGF-β1 on articular cartilage repair in a rabbit osteochondral defect model.
J Biomed Mater Res B Appl Biomater, 105(8), 2592-2602, 2017.
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軟骨再生（Cartilage Regeneration）
- 内山綾香, 豊田恵利子, 濱橋恒介, 和才志帆, 大村はるか, 玉木美夕, 小川真, 田中竜実, 岸達也, 渡辺正彦, 佐藤正人
異なるキットで作製した多血小板血漿(PRP)の作用機序の検討
臨床整形外科, 第59巻, 9月号, 2024
- Ryoka Uchiyama, Haruka Omura, Miki Maehara, Eriko Toyoda, Miyu Tamaki, Makoto Ogawa, Tatsumi Tanaka, Masahiko Watanabe and Masato Sato
Effect of Freeze-Thawing Treatment on Platelet-Rich Plasma Purified with Different Kits
International journal of Molecular Sciences, 25(18), 9981, 2024
- Yasuyuki Sogo, Eriko Toyoda, Toshihiro Nagai, Takumi Takahashi, Daichi Takizawa, Masahiko Watanabe, Masato Sato
Disease-Modifying Effects of Lenvatinib, a Multiple Receptor Tyrosine Kinase Inhibitor, on Posttraumatic Osteoarthritis of the Knee
International journal of Molecular Sciences, 25(12), 6514, 2024
- Y.Hosono,A.Kuwasawa,E.Toyoda,K.Nihei,S.Sato,M.Watanabe,M.Sato
Multiple intra-articular injections with adipose-derived stem cells for knee osteoarthritis cause severe arthritis with anti-histone H2B antibody production
Regenerative Therapy. Vol,24. December, 2023
- Uchiyama R, Toyoda E, Maehara M, Wasai S, Omura H, Watanabe M, Sato M
Effect of Platelet-Rich Plasma on M1/M2 Macrophage Polarization.
Int. J. Mol. Sci, 22(5), 2021.
- Toyoda E, Maehara M, Watanabe M, Sato M
Candidates for Intra-Articular Administration Therapeutics and Therapies of Osteoarthritis.
Int. J. Mol. Sci. 22(7), 2021.
- Maehara M, Toyoda E, Takahashi T, Watanabe M, Sato M
Potential of Exosomes for Diagnosis and Treatment of Joint Disease: Towards a
Point-of-Care Therapy for Osteoarthritis of the Knee.
Int. J. Mol. Sci, 22(5), 2021.
- 和才志帆, 前原美樹, 内山綾香, 岡田恵里, 渡辺雅彦, 佐藤正人
自己蛋白質溶液.
関節外科 基礎と臨床, 39(9), 956-961, 2020.
- Wasai S, Sato M, Maehara M, Toyoda E, Uchiyama R, Takahashi T, Okada E, Iwasaki Y, Suzuki S, Watanabe M
Characteristics of autologous protein solution and leucocytepoor platelet-rich plasma for the treatment of osteoarthritis of the knee.
Scientific Reports, 10:10572, 2020.
- 和才志帆, 佐藤正人, 前原美樹, 内山綾香, 渡辺雅彦
変形性膝関節症に対する多血小板血漿（PRP）治療：自験例に基づく基礎と臨床.
Bone Joint Nerve, 10(2), 193-196, 2020.
- 佐藤正人
「アンメットメディカルニーズに応える」とは？
再生医療, 19(1), 11, 2020.
- 佐藤正人
再生医療の現状とスポーツ医学への応用.
臨床スポーツ医学, 37(1), 2020.
- 和才志帆, 佐藤正人, 前原美樹, 渡辺雅彦
変形性膝関節症に対する多血小板血漿療法.
別冊整形外科, 76, 98-103, 2019.
- Toyoda E, Sato M, Takahashi T, Maehara M, Nakamura Y, Mitani G, Takagaki T, Hamahashi K, Watanabe M
Multilineage-differentiating stress-enduring (Muse)-like cells exist in synovial tissue.
Regenerative Therapy, 10, 17-26, 2019.
- Tani Y, Sato M, Yokoyama M, Yokoyama M, Takahashi T, Toyoda E, Okada E, Fujimura S, Maruki H, Kato Y, Yamato M, Okano T, Mochida J
Intra-articular administration of EP2 enhances the articular cartilage repair in a rabbit model.
J Tissue Eng Regen Med, [Epub ahead of print] 2018.
- Yokoyama M, Sato M, Tani Y, Yokoyama M, Kokubo M, Yamato M, Okano T, Mochida J
Platelet-activated serum might have a therapeutic effect on damaged articular cartilage.
J Tissue Eng Regen Med, 11(12), 3305-3312, 2017.
- 長井敏洋, 佐藤正人
膝OAに対するVEGF阻害剤の効果.
Bone Joint Nerve, 6(3), 589-594, 2016.
- Takagaki T, Sato M, Kawake T, Baba T, Kihira K, Mochida J
Interactions between jellyfish mucin and hyaluronan in human chondrocytes.
International Journal of Biological & Pharmaceutical Research 6, 351-358, 2015.
- Nagai T, Sato M, Kobayashi M, Yokoyama M, Tani Y, Mochida J
Bevacizumab, an anti-vascular endothelial growth factor antibody, inhibits osteoarthritis.
Arthritis Research & Therapy 16(5): 427, 2014.
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軟骨評価法（Diagnostic Methods for Cartilage）
- Ukai T, Sato M, Wasai S, Takahashi T, Omura H, Watanabe M.
Comparison of properties determined using electromechanical assessment (Arthro-BSTTM) with macroscopic and histological properties in symptomatic human articular cartilage of the hip.
Arthritis Reseach & Therapy, 23.227, 2021.9.
- Takahashi T, Sato M, Toyoda E, Maehara M, Takizawa D, Maruki H, Tominaga A, Okada E, Okazaki K, Watanabe M
Rabbit xenogeneic transplantation model for evaluating human chondrocyte sheets used in articular cartilage repair.
J Tissue Eng Regen Med, 12, 2067-2076, 2018.
- 高橋匠, 佐藤正人
関節軟骨再生の臨床応用を踏まえた前臨床研究におけるエビデンス構築‐動物モデル選択‐.
関節外科 基礎と臨床, 36(12), 1212-1217, 2017.
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